Europe. The EMEA has recommended the suspension of the marketing authorization of a system (Ionsys) for the transdermal delivery of fentanyl, an opioid analgesic. This drug delivery system marketed by Janssen-Cilag International NV, has a defect that could lead to patients being overdosed. It has been authorized in the European Union (EU) since January 2006 [...]

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The most common way of managing the pain that accompanies inflammation is to use drugs such as aspirin and ibuprofen. These work by selectively blocking the protein COX2, which functions to produce soluble molecules known as prostaglandins.

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Minimal Criteria 1.  A compelling urge to move the limbs, usually associated with paresthesias or dysesthesias 2.  Motor restlessness as seen in activities such as floor pacing, tossing and turning in bed and rubbing the legs 3.  Symptoms that are worse or present only during rest and are partially or temporarily relieved by activity 4.  [...]

Continue reading about Diagnostic Criteria and Associated Features of Restless Legs Syndrome (RLS)

Dott. Luigi Vicari on gennaio 7th, 2009

The word dermatome refers to a correspondence between the skin and the nervous system.  Sensory dermatome maps used to help localize the level of neurologic deficit.

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Abstral® is an important new treatment option for inadequately controlled breakthrough cancer pain (BTcP) in opioid-tolerant cancer patients. The Abstral formulation delivers the analgesic power of fentanyl in a fast dissolving sublingual tablet. Abstral provides rapid relief of BTcP from 10 minutes1, provides predictable dosing2,3 and is convenient and easy to use.

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Dott. Luigi Vicari on gennaio 4th, 2009

Convincing evidence to recommend antioxidants for treatment has been  lacking  Bethesda, MD (Jan. 1, 2009) Antioxidant supplementation was found to be effective in relieving pain and reducing levels of oxidative stress in patients with chronic pancreatitis (CP), reports a new study in Gastroenterology.

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Dott. Luigi Vicari on gennaio 1st, 2009

December 30, 2008 — A new study extends to 4 years the previously published 2-year results of research that found that spine surgery provides more rapid and greater relief in symptoms and a greater improvement in function than nonsurgical interventions for patients with lumbar disk herniation. And while the surgery did not get patients back [...]

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Dott. Luigi Vicari on gennaio 1st, 2009

Continue reading about Auguri di Buon Natale e Felice Anno Nuovo